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UNC13A antibody

Product Specifications

Background

UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.

Synonyms

Protein unc-13 homolog A|Munc13-1|UNC13A|KIAA1032

Gene ID

23025

UniProt

Q9UPW8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

unc-13 homolog A(C. elegans)

Target

UNC13A

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Neuroscience, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

193 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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