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GABRG2 Antibody - N-terminal region : Biotin (AVARP13033_P050-Biotin)

Selected Variant

AVARP13033_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Gamma-aminobutyric acid (GABA) A receptor, gamma 2

Gene Aliases

CAE2, ECA2, FEB8, DEE74, EIEE74, GEFSP3

Gene ID

2566

Swiss Prot

Q5REA1

Accession Number

NP_000807

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GABRG2

Target

GABRG2 is a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Partner Proteins

ZDHHC3; GABARAP; PRKCB; PRKCA; GABRG2; DRD5; PPP3CA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Selmer, K.K., (2008) Acta Neurol. Scand. 117 (4), 289-292

Shipping Conditions

Wet Ice

Protein Length

467

NCBI Gene Symbol

GABRG2

NCBI GB Accession Number

GABRG2

Host or Source

Rabbit

Protein Name

Gamma-aminobutyric acid receptor subunit gamma-2

Nucleotide Accession Number

NM_000816

Peptide Sequence

GFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDI

Subunit

Gamma-2

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