CDC25A Antibody - middle region : HRP (AVARP03040_P050-HRP)

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

ANAPC11; FZR1; FBXW11; BTRC; CUL1; SKP1; VCP; UBC; NPLOC4; YWHAQ; SCYL1; CAMK1D; POLR1D; FGF21; CHEK2; CCNI; MCM3AP; VAMP8; CUL3; XPO1; SOX5; PEX19; NFYA; NFKBIB; MTAP; SMAD3; LMO2; IL3RA; HLA-C; FTH1; EEF1A1; DMD; CHEK1; APP; TRIB3; CSNK1A1; CDK2; FAM193

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.