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CCNG2 Antibody - N-terminal region : FITC (AVARP03032_T100-FITC)

Selected Variant

AVARP03032_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Cyclin G2

Gene ID

901

Swiss Prot

Q16589

Accession Number

NP_004345

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CCNG2

Target

The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.

Partner Proteins

EFHC2; FAM208B; NRIP2; UBC; SKP2; SKP1; PPP2CA; PPP2R4; PPP2R5C; PPP2R5B

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 91%; Dog: 91%; Human: 100%; Mouse: 83%; Rat: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Bennin, D.A., et al., (2002) J. Biol. Chem. 277 (30), 27449-27467

Shipping Conditions

Wet Ice

Protein Length

344

NCBI Gene Symbol

CCNG2

NCBI GB Accession Number

CCNG2

Host or Source

Rabbit

Protein Name

Cyclin-G2

Nucleotide Accession Number

NM_004354

Peptide Sequence

MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNT

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