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HIST1H4A Antibody - N-terminal region : FITC (ARP70540_P050-FITC)

Selected Variant

ARP70540_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FA, H4-16, H4C11, H4C12, H4C13, H4C14, H4C15, HIST1H4A

Gene ID

8359

Swiss Prot

P62805

Accession Number

NP_778224

Host

Rabbit

Reactivity

Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H4A

Target

HIST1H4A is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Partner Proteins

UBC; DTX3L; RBBP4; H3F3A; CENPA; HIST1H3A; HDAC2; ASB9; ASB16; L3MBTL2; rev; ARFIP1; JMJD6; XPO7; FAF1; HSPH1; SEC23A; PRMT3; RBX1; HIRIP3; CUL1; ZYX; SF1; TTC1; TROVE2; SHMT1; RPL24; PPM1G; OSBP; GFPT1; GARS; CARS; FBXO6; PAN2; PRMT8; RL1; HCVgp1; ITGA4

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

11kDa

Shipping Conditions

Wet Ice

Protein Length

103

NCBI Gene Symbol

HIST1H4A

NCBI GB Accession Number

HIST1H4A

Host or Source

Rabbit

Protein Name

Histone H4

Nucleotide Accession Number

NM_175054

Peptide Sequence

LGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLK

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