PE Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (ζ-chain) to generate an activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CD3E, T3E
Swiss Prot
P07766 Human
Cellular Locus
Cell membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within
Isotype
IgG1
Clone
PSH04-92
Conjugation
PE
Type
Recombinant Mouse monoclonal Antibody
Applications
FC
Positive Control
Human peripheral blood lymphocytes.
Dilution
FC: 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Supplied in phosphate-buffered solution, pH 7.2, containing 0.2% ProClean 950 and BSA.
Molecular Weight
Predicted band size: 23 kDa
Storage Conditions
Store at 2°C to 8°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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