PE Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (ζ-chain) to generate an activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex.
Product Specifications
Product Name Alternative
Abbreviation
CD3E, T3E
Swiss Prot
P07766 Human
Cellular Locus
Cell membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within
Isotype
IgG1
Clone
PSH04-92
Conjugation
PE
Type
Recombinant Mouse monoclonal Antibody
Applications
FC
Positive Control
Human peripheral blood lymphocytes.
Dilution
FC: 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Supplied in phosphate-buffered solution, pH 7.2, containing 0.2% ProClean 950 and BSA.
Molecular Weight
Predicted band size: 23 kDa
Storage Conditions
Store at 2°C to 8°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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