Fenpropimorph

Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells[1][2][3].

Product Specifications

CAS Number

[67564-91-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H361, H411

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fenpropimorph.html

Purity

98.74

Solubility

DMF : 15 mg/mL (ultrasonic; warming)

Smiles

C[C@H](O[C@@H](C1)C)CN1CC(C)CC2=CC=C(C=C2)C(C)(C)C

Molecular Formula

C20H33NO

Molecular Weight

303.48

Precautions

H302, H315, H361, H411

References & Citations

[1]Costet MF, et al. Ecdysteroid biosynthesis and embryonic development are disturbed in insects (Locusta migratoria) reared on plant diet (Triticum sativum) with a selectively modified sterol profile. Proc Natl Acad Sci U S A. 1987;84 (3) :643-647.|[2]Marcireau C, et al. In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property. Antimicrob Agents Chemother. 1990;34 (6) :989-993.|[3]Corio-Costet MF, et al. Inhibition by the fungicide fenpropimorph of cholesterol biosynthesis in 3T3 fibroblasts. Biochem J. 1988;256 (3) :829-834.