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PACS1 Antibody - C-terminal region : FITC (ARP64805_P050-FITC)

Selected Variant

ARP64805_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Phosphofurin acidic cluster sorting protein 1

Gene Aliases

SHMS, MRD17

Gene ID

55690

Swiss Prot

Q6VY07

Accession Number

AAH09936

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.

Partner Proteins

UBC; GGA3; CSNK2A1; FGFR1OP; PPP2CA; VAMP4; CLCN7; PPP2CB; PKD2; JUN; IGF2R; FURIN; TRPV4; nef

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42kDa

Shipping Conditions

Wet Ice

Protein Length

366

NCBI Gene Symbol

PACS1

NCBI GB Accession Number

PACS1

Host or Source

Rabbit

Protein Name

Phosphofurin acidic cluster sorting protein 1

Nucleotide Accession Number

NM_018026

Peptide Sequence

FLSKKPREKEVDSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFF

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