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TXNRD3 Antibody - N-terminal region : HRP (ARP64748_P050-HRP)

Product Specifications

Gene Name

Thioredoxin reductase 3

Gene Aliases

TGR, TR2, TRXR3, TR2IT1, TXNRD3NB, TXNRD3IT1, TXNRD3NT1

Gene ID

114112

Swiss Prot

Q86VQ6

Accession Number

NP_443115

Host

Rabbit

Reactivity

Human, Mouse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human TXNRD3

Target

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 86%; Rabbit: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-TXNRD3 (ARP64748_P050-HRP) antibody

Protein Length

643

NCBI Gene Symbol

TXNRD3

NCBI GB Accession Number

TXNRD3

Host or Source

Rabbit

Protein Name

Thioredoxin reductase 3

Nucleotide Accession Number

NM_052883

Peptide Sequence

LSPPGRRARLSSPGPSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHST

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