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LAMTOR3 Antibody - N-terminal region : HRP (ARP60324_P050-HRP)

Selected Variant

ARP60324_P050-HRP

Size: 100 µL

Product Specifications

Gene Aliases

MP1, MAPBP, MAPKSP1, PRO0633, MAP2K1IP1, Ragulator3

Gene ID

8649

Swiss Prot

Q9UHA4

Accession Number

NP_068805

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human LAMTOR3

Target

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.

Partner Proteins

NIF3L1; LAMTOR2; IBTK; MBD2; BHMT; PEF1; C19orf70; MRPL43; PRR3; LPCAT1; MRPS9; MRPS35; MRPL47; TOMM22; DDX28; TSR1; RNMTL1; LAMTOR1; NDUFB11; TMCO1; MRPL39; PTRH2; RAB14; MRPL51; MRPL22; UQCRQ; PUF60; RAB31; TOMM40; MSLN; TOMM70A; NUPL1; SPCS2; PICALM; V

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

LAMTOR3 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

13kDa

Shipping Conditions

Wet Ice

Protein Length

124

NCBI Gene Symbol

LAMTOR3

NCBI GB Accession Number

LAMTOR3

Host or Source

Rabbit

Protein Name

Ragulator complex protein LAMTOR3

Nucleotide Accession Number

NM_021970

Peptide Sequence

LPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSK

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