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IMPA1 Antibody - middle region : HRP (ARP58713_P050-HRP)

Selected Variant

ARP58713_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Inositol (myo) -1 (or 4) -monophosphatase 1

Gene Aliases

IMP, IMPA, MRT59

Gene ID

3612

Swiss Prot

P29218

Accession Number

NP_005527

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IMPA1

Target

IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. IMPA1 can use myo-inositol monophosphates, myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.

Partner Proteins

IMPA2; IMPA1; SUMO2; UBC; S100B; nxf1; sbr; nxf-1; mex67; ELAVL1; CALB1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 85%; Pig: 93%; Rabbit: 79%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Ohnishi, T., (2007) J. Biol. Chem. 282 (1), 637-646

Shipping Conditions

Wet Ice

Protein Length

277

NCBI Gene Symbol

IMPA1

NCBI GB Accession Number

IMPA1

Host or Source

Rabbit

Protein Name

Inositol monophosphatase 1

Nucleotide Accession Number

NM_005536

Peptide Sequence

IVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE

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