CEBPB Antibody - N-terminal region : Biotin (ARP57940_P050-Biotin)

Product Specifications

Gene Name

CCAAT/enhancer binding protein (C/EBP), beta

Gene Aliases

TCF5, IL6DBP, NF-IL6, C/EBP-beta

Gene ID

1051

Swiss Prot

P17676

Accession Number

NP_005185

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPB

Target

CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

CEBPA; UBC; EGR1; EP300; TP63; RB1; RELA; DAXX; CASP8; CASP1; SMARCA2; HDAC1; SMARCC1; SMARCB1; SMARCA4; SMARCA5; TAF9; ELAVL1; SUMO2; TRIM28; CEBPB; ATF3; CARM1; GSK3B; SUMO1; KAT2A; HDAC9; KAT2B; NCOR2; NCOR1; STAT3; PPARG; NRF1; CREBBP; ATF2; EHMT2; SP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

CEBPB is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 92%; Human: 100%; Pig: 100%; Rabbit: 100%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.