Recombinant HER4 / ErbB4 (682-993) Protein

<strong>Recombinant HER4 / ErbB4 (682-993) Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017528_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 36.6 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> N/A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Patel NV, Acarregui MJ, Snyder JM, Klein JM, Sliwkowski MX, Kern JA. Neuregulin-1 and human epidermal growth factor receptors 2 and 3 play a role in human lung development in vitro Am J Respir Cell Mol Biol. 2000 Apr;22(4):432-40._x000D_ 2: Vartanian T, Goodearl A, Viehöver A, Fischbach G. Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3 J Cell Biol. 1997 Apr 7;137(1):211-20._x000D_ 3: Elenius K, Paul S, Allison G, Sun J, Klagsbrun M. Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation EMBO J. 1997 Mar 17;16(6):1268-78._x000D_ 4: Culouscou JM, Plowman GD, Carlton GW, Green JM, Shoyab M. Characterization of a breast cancer cell differentiation factor that specifically activates the HER4/p180erbB4 receptor J Biol Chem. 1993 Sep 5;268(25):18407-10._x000D_ 5: De Potter IY, Poumay Y, Squillace KA, Pittelkow MR. Human EGF receptor (HER) family and heregulin members are differentially expressed in epidermal keratinocytes and modulate differentiation Exp Cell Res. 2001 Dec 10;271(2):315-28._x000D_ 6: Chan SD, Antoniucci DM, Fok KS, Alajoki ML, Harkins RN, Thompson SA, Wada HG. Heregulin activation of extracellular acidification in mammary carcinoma cells is associated with expression of HER2 and HER3 J Biol Chem. 1995 Sep 22;270(38):22608-13._x000D_ 7: Leach RE, Kilburn BA, Petkova A, Romero R, Armant DR. Diminished survival of human cytotrophoblast cells exposed to hypoxia/reoxygenation injury and associated reduction of heparin-binding epidermal growth factor-like growth factor Am J Obstet Gynecol. 2008 Apr;198(4):471.e1-7; discussion 471.e7-8._x000D_ 8: Landgraf R, Pegram M, Slamon DJ, Eisenberg D. Cytotoxicity and specificity of directed toxins composed of diphtheria toxin and the EGF-like domain of heregulin beta1 Biochemistry. 1998 Mar 3;37(9):3220-8._x000D_ 9: Zhang K, Sun J, Liu N, Wen D, Chang D, Thomason A, Yoshinaga SK. Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2 J Biol Chem. 1996 Feb 16;271(7):3884-90._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8570211">10: Riese DJ 2nd, Bermingham Y, van Raaij TM, Buckley S, Plowman GD, Stern DF. Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-beta Oncogene. 1996 Jan 18;12(2):345-53.</a>_x000D_ _x000D_ <strong>Products Related to Recombinant HER4 / ErbB4 (682-993) Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>