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OPA1 Antibody - N-terminal region : Biotin (ARP57715_P050-Biotin)

Product Specifications

Gene Name

Optic atrophy 1 (autosomal dominant)

Gene Aliases

NPG, NTG, MGM1, BERHS, largeG, MTDPS14

Gene ID

4976

Swiss Prot

E5KLK2

Accession Number

NP_570844

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; PARK2; MYC; HSP90AA5P; NIT2; HTRA2; NPTX1; NDUFS8; NDUFS1; NDUFA9; ILF3; HADHB; ECH1; DNASE2; APP; SMAD3; SMAD2; CAND1; CUL3; ELAVL1; MME

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

102kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-OPA1 (ARP57715_P050-Biotin) antibody

Protein Length

924

NCBI Gene Symbol

OPA1

NCBI GB Accession Number

OPA1

Host or Source

Rabbit

Protein Name

Mitochondrial dynamin-like 120 kDa protein EMBL ADP90061.1

Nucleotide Accession Number

NM_130831

Peptide Sequence

SPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERL

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