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IP10 Recombinant Rabbit Monoclonal Antibody [JA10-82]

Chemokines are members of a superfamily of inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20% to 50% homology in their predicted amino acid sequences and are divided into four subfamilies: C-C, C-X-C, C and C-X3-C. In the C-X-C or α subfamily, the first two of four cysteine motifs are separated by another amino acid residue. In the second subfamily, designated C-C or β, the first cysteines are adjacent. C subfamily members, also designated γ chemokines, lack the first and third cysteine residues of the conserved motif. In the C-X3-C, or δ subfamily, members have three amino acids between the two cysteines. The C-X-C chemokine subfamily includes IL-8, GROα/β/γ (and the murine homologs KC, MIP-2α and MIP-2β), platelet basic protein, ENA-78, GCP-2, PF4, IP-10 (and its murine homolog, CRG) and MIG.

Product Specifications

Product Name Alternative

Interferon gamma induced factor MOB1, mouse, homolog of antibody Interferon gamma induced protein 10 antibody 10 kDa interferon gamma induced protein antibody 10 kDa interferon gamma-induced protein antibody C X C motif chemokine 10 antibody C7 antibody Chemokine (C X C motif) ligand 10 antibody Chemokine CXC motif ligand 10 antibody Crg 2 antibody CRG2 antibody CXCL10 antibody CXCL10 (1-73) antibody CXL10_HUMAN antibody Gamma IP10 antibody Gamma-IP10 antibody gIP 10 antibody GIP10 antibody IFI10 antibody INP 10 antibody INP10 antibody Interferon activated gene 10 antibody Interferon activated gene 10 antibody Interferon gamma induced cell line antibody Interferon inducible cytokine IP 10 antibody Interferon inducible cytokine IP10 antibody IP 10 antibody IP-10 antibody Mob 1 antibody MOB1 antibody Protein 10 from interferon (gamma) induced cell line antibody SCYB10 antibody Small inducible cytokine B10 antibody Small inducible cytokine B10 precursor antibody Small inducible cytokine subfamily B (Cys X Cys) member 10 antibody Small inducible cytokine subfamily B CXC member 10 antibody Small inducible cytokine subfamily B, member 10 antibody Small-inducible cytokine B10 antibody

Abbreviation

Gamma-IP10, IP-10, CXCL10

Swiss Prot

P02778 Human

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human IP10 aa 49-98 / 98.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P

Positive Control

THP-1 treated with 100ng/mL IFN-γ for 24 hours then 300ng/mL Brefeldin A for 20 hours cell lysate, THP-1 treated with 200ng/mL IFN-γ and 50ng/mL LPS for 24 hours cell lysate, HepG2, SH-SY5Y, human skin tissue, human tonsil tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:50-1:100 ;IF-Tissue: 1:50-1:100 ;IHC-P: 1:50-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 11 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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