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ARSA Antibody - N-terminal region : HRP (ARP54528_P050-HRP)

Selected Variant

ARP54528_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Arylsulfatase A

Gene Aliases

ASA, MLD

Gene ID

410

Swiss Prot

P15289

Accession Number

NP_000478

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ARSA

Target

ARSA hydrolyzes cerebroside sulfate. Defects in ARSA are a cause of leukodystrophy metachromatic (MLD) .The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.

Partner Proteins

TRIP13; PPIC; CETN2; CLEC4G; ARSA; GAL3ST1; BMPR2; CTSL

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Saito, S., (2008) Mol. Genet. Metab. 93 (4), 419-425

Shipping Conditions

Wet Ice

Protein Length

507

NCBI Gene Symbol

ARSA

NCBI GB Accession Number

ARSA

Host or Source

Rabbit

Protein Name

Arylsulfatase A

Nucleotide Accession Number

NM_000487

Peptide Sequence

DLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVR

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