SETMAR Antibody - C-terminal region: HRP (ARP51245_P050-HRP)
Product Specifications
Gene Name
SET domain and mariner transposase fusion gene
Gene Aliases
Mar1, METNASE
Gene ID
6419
Swiss Prot
E7EN68
Accession Number
NP_001230652
Host
Rabbit
Reactivity
Human, Cow
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human SETMAR
Target
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.
Partner Proteins
CHEK1; H3F3C; tat; PRPF19; SETMAR; RAD9A; PCNA; TOP2A; XRCC4
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
59kDa
Shipping Conditions
Wet Ice
Protein Length
545
NCBI Gene Symbol
SETMAR
Protein Name
Histone-lysine N-methyltransferase Ensembl ENSP00000403145
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