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Clusterin Recombinant Rabbit Monoclonal Antibody [PSH04-33]

Clusterin (apolipoprotein J) is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging.

Product Specifications

Product Name Alternative

40 antibody AAG 4 antibody AAG4 antibody Aging associated protein 4 antibody Aging-associated gene 4 protein antibody AI893575 antibody APO J antibody Apo-J antibody APOJ antibody ApoJalpha antibody ApoJbeta antibody Apolipoprotein J antibody ApolipoproteinJ antibody CLI antibody CLU antibody CLU1 antibody CLU2 antibody CLUS_HUMAN antibody Clusterin alpha chain antibody Clusterin antibody Clusterin beta chain antibody Complement associated protein SP 40 40 antibody Complement associated protein SP 40 antibody Complement associated protein SP40 antibody Complement cytolysis inhibitor a chain antibody Complement cytolysis inhibitor antibody Complement cytolysis inhibitor b chain antibody Complement lysis inhibitor antibody Complement-associated protein SP-40 antibody D14Ucla3 antibody Dimeric acid glycoprotein antibody Glycoprotein 80 antibody Glycoprotein III antibody GP80 antibody Ku70-binding protein 1 antibody KUB 1 antibody KUB1 antibody MGC24903 antibody NA1/NA2 antibody RATTRPM2B antibody SGP 2 antibody SGP2 antibody SP 40 antibody SP40 antibody Sugp-2 antibody Sulfated glycoprotein 2 antibody Testosterone repressed prostate message 2 antibody Testosterone-repressed prostate message 2 antibody TRPM 2 antibody TRPM-2 antibody TRPM2 antibody TRPM2B antibody Trpmb antibody

Abbreviation

CLU, APOJ, CLI, KUB1, AAG4

Swiss Prot

P10909 Human

Cellular Locus

Nucleus, Cytoplasm, Mitochondrion membrane, cytosol, Microsome, Endoplasmic reticulum, Mitochondrion, perinuclear region, Cytoplasmic vesicle, secretory vesicle, chromaffin granule.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within human Clusterin aa 400-449 / 449.

Isotype

IgG

Clone

PSH04-33

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

HeLa cell lysate, SK-Br-3 cell lysate, A431 cell lysate, PANC-1 cell lysate, MCF7 cell lysate, T-47D cell lysate, human lung cancer tissue, human prostate cancer tissue, human pancreas tissue, human tonsil tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:8,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 52 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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