NCAPD2 Antibody - C-terminal region : Biotin (ARP46210_P050-Biotin)

Product Specifications

Gene Name

Non-SMC condensin I complex, subunit D2

Gene Aliases

CNAP1, CAP-D2, MCPH21, hCAP-D2

Gene ID

9918

Swiss Prot

Q15021

Accession Number

NP_055680

Host

Rabbit

Reactivity

Human, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NCAPD2

Target

NCAPD2 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. NCAPD2 may target the condensin complex to DNA via its C-terminal domain.

Partner Proteins

UBC; NCAPG; CCAR2; NCAPH; SMC2; SMC4; TXNL1; RABEP1; PABPC4; RPS5; FLNC; SOX2; CSNK2A1; PAXIP1; PNPT1; NUP153; MEA1; HSPD1; C1QBP; SIRT7; CDK1; RAD21; SIRT3; tat; PARP1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

NCAPD2 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Dog: 79%; Horse: 93%; Human: 100%; Pig: 92%; Rabbit: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.