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CTH Antibody - N-terminal region : Biotin (ARP46067_P050-Biotin)

Product Specifications

Gene Name

Cystathionase (cystathionine gamma-lyase)

Gene Aliases

MGC9471

Gene ID

1491

Swiss Prot

P32929

Accession Number

NP_001893

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CTH

Target

CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Partner Proteins

GUCD1; WDYHV1; RECK; CTH; PTMA; GMDS; CAPN2; ATIC; SDCBP2; UBC; ELAVL1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Moore, L.E., (2007) Int. J. Cancer 120 (11), 2452-2458

Shipping Conditions

Wet Ice

Protein Length

405

NCBI Gene Symbol

CTH

NCBI GB Accession Number

CTH

Host or Source

Rabbit

Protein Name

Cystathionine gamma-lyase

Nucleotide Accession Number

NM_001902

Peptide Sequence

VPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAF

Frequently Asked Questions

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