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EGFR Antibody (phospho-Y1069)

Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation.

Product Specifications

CAS Number

9007-83-4

UniProt

P00533

Host

Rabbit

Immunogen

This p-EGFR antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY1069 of human EGFR.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, DB, ELISA

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the p-EGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This p-EGFR antibody is available for research use only.

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