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SBDS Antibody - N-terminal region : Biotin (ARP45719_T100-Biotin)

Selected Variant

ARP45719_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Shwachman-Bodian-Diamond syndrome

Gene Aliases

SDS, SDO1, SWDS, CGI-97

Gene ID

51119

Swiss Prot

Q9Y3A5

Accession Number

NP_057122

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SBDS

Target

SBDS is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. Mutations within its gene are associated with Shwachman-Bodian-Diamond syndrome.This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located.

Partner Proteins

SUMO2; TYMS; PNP; IDH1; GOT1; UBC; CHAMP1; MPLKIP; MRPL53; SARNP; SLIRP; SRPRB; ACOT13; SRRM2; TIMM44; TOMM40; UBE4B; SCO2; SNX3; STX7; SF1; VDAC3; TIAL1; SPR; RBMS1; NDUFA7; NDUFA2; IDH3G; STOM; ACAA1; ACD; TERF2IP; POT1; TERF1; CLN3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Austin, K.M., (2005) Blood 106 (4), 1253-1258

Shipping Conditions

Wet Ice

Protein Length

250

NCBI Gene Symbol

SBDS

NCBI GB Accession Number

SBDS

Host or Source

Rabbit

Protein Name

Ribosome maturation protein SBDS

Nucleotide Accession Number

NM_016038

Peptide Sequence

LQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKER

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