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RRBP1 Antibody - N-terminal region : FITC (ARP44952_P050-FITC)

Selected Variant

ARP44952_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Ribosome binding protein 1 homolog 180kDa (dog)

Gene Aliases

RRp, hES, p180, ES130, ES/130

Gene ID

6238

Swiss Prot

Q9P2E9-3

Accession Number

NP_001036041

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RRBP1

Target

Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome.Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. Alternate splicing results in multiple transcript variants.

Partner Proteins

VCP; UBC; MDM2; LGR4; TARDBP; IQCB1; MAP1LC3A; PRKD2; SMAD9; MRPL53; SRPRB; CDV3; CHMP2A; PPIF; PQBP1; SCP2; RPS19; RPL38; RBMS1; PIN4; NDUFA7; HNRNPM; RAB8A; ILF3; HSPA1L; HSBP1; KLF5; CUL3; KIAA0101; SUMO1; Ndc80; ZWINT; ATF7IP; KIF5B; DSTN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RRBP1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 82%; Dog: 81%; Guinea Pig: 76%; Horse: 92%; Human: 100%; Mouse: 75%; Rabbit: 81%; Rat: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

109kDa

References & Citations

Parma, J., (2007) Mol. Biol. Cell 18 (10), 3741-3751

Shipping Conditions

Wet Ice

Protein Length

977

NCBI Gene Symbol

RRBP1

NCBI GB Accession Number

RRBP1

Host or Source

Rabbit

Protein Name

Ribosome-binding protein 1

Nucleotide Accession Number

NM_001042576

Peptide Sequence

TDVAQSPEAPKQEAPAKKKSGSKKKGPPDADGPLYLPYKTLVSTVGSMVF

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