KRT18 Antibody - N-terminal region: Biotin (ARP40205_T100-Biotin)
Product Specifications
Gene Name
Keratin 18
Gene Aliases
K18, CK-18, CYK18
Gene ID
3875
Swiss Prot
P05783
Accession Number
NP_000215
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human KRT18
Target
KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Partner Proteins
KRT18; GOLGA2; UBC; HAUS1; CCDC146; MDM2; EED; HNRNPU; FLII; FKBP3; DDX1; C14orf166; RTCB; CNOT1; SEC16A; RPL14; RFC2; UPF2; BBS7; PAN2; BBS4; BBS2; BBS1; SMARCD1; ORC5; NOS2; KRT8; KPNA2; ITGA4; HRAS; GRN; FN1; EP300; ATF2; CDH1; CDC5L; YTHDC1; PIAS4; TX
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
KRT18 is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 92%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47kDa
Shipping Conditions
Wet Ice
Protein Length
430
NCBI Gene Symbol
KRT18
Protein Name
Keratin, type I cytoskeletal 18
Nucleotide Accession Number
NM_000224
Curated Selection
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