TFEB Antibody - C-terminal region : Biotin (ARP38810_T100-Biotin)
Selected Variant
ARP38810_T100-Biotin
Size: 100 µL
Product Specifications
Gene Name
Transcription factor EB
Gene Aliases
TCFEB, BHLHE35, ALPHATFEB
Gene ID
7942
Swiss Prot
P19484
Accession Number
NP_009093
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TFEB
Target
TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t (6;11) (p21; q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Partner Proteins
SRPK1; YWHAQ; TFEC; TFE3; MITF
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Goat: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 85%; Yeast: 100%; Zebrafish: 91%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
53kDa
References & Citations
Argani, P., et al., (2005) Am. J. Surg. Pathol. 29 (2), 230-240
Shipping Conditions
Wet Ice
Protein Length
476
NCBI Gene Symbol
TFEB
NCBI GB Accession Number
TFEB
Host or Source
Rabbit
Protein Name
Transcription factor EB
Nucleotide Accession Number
NM_007162
Peptide Sequence
SLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL
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