PTH1R Recombinant Rabbit Monoclonal Antibody [JE36-10]
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Product Specifications
Product Name Alternative
Abbreviation
PTH1R, PTHR, PTHR1
Swiss Prot
Q03431 Human
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human PTH1R aa 39-188 / 593.
Isotype
IgG
Clone
JE36-10
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HeLa cell lysate, HepG2 cell lysate, MCF7 cell lysate, THP-1 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 66 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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