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Noto Antibody - N-terminal region : FITC (ARP36811_P050-FITC)

Selected Variant

ARP36811_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Notochord homolog (Xenopus laevis)

Gene Aliases

N, Fl, tc, Flh, MmN, Not, MmNot

Gene ID

384452

Swiss Prot

A8MTQ0

Accession Number

NP_001007473

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the n terminal region of mouse Noto

Target

Noto is a transcription regulator acting downstream of both FOXA2 and T during notochord development.Noto is required for node morphogenesis.Noto is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 85%; Guinea Pig: 93%; Human: 93%; Mouse: 100%; Rabbit: 92%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

26kDa

Shipping Conditions

Wet Ice

Protein Length

240

NCBI Gene Symbol

NOTO

NCBI GB Accession Number

Noto

Host or Source

Rabbit

Protein Name

Homeobox protein notochord

Nucleotide Accession Number

NM_001007472

Peptide Sequence

VQPGSLRPCPGAVSPVVPRRLARGRLESSFSVEAILARPKTRELAATSLP

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