Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH07-45]
Von Willebrand factor (VWF) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic purpura, Heyde's syndrome, and possibly hemolytic–uremic syndrome. Increased plasma levels in many cardiovascular, neoplastic, metabolic (e.g. diabetes), and connective tissue diseases are presumed to arise from adverse changes to the endothelium, and may predict an increased risk of thrombosis.
Product Specifications
Product Name Alternative
Abbreviation
VWF, F8VWF
Swiss Prot
P04275 Human, Q8CIZ8 Mouse, Q62935 Rat
Cellular Locus
Secreted, extracellular space, extracellular matrix.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human Von Willebrand Factor aa 734-1,283.
Isotype
IgG
Clone
PSH07-45
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue, IP
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:5,000 ;IHC-P: 1:500 ;IF-Tissue: 1:100 ;IP: 1-2μg/sample
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 309 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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