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SCN8A Antibody - middle region : Biotin (ARP35227_P050-Biotin)

Product Specifications

Gene Name

Sodium channel, voltage gated, type VIII, alpha subunit

Gene Aliases

MED, PN4, CIAT, BFIS5, DEE13, NaCh6, CERIII, EIEE13, MYOCL2, Nav1.6

Gene ID

6334

Swiss Prot

Q9UQD0

Accession Number

NP_055006

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SCN8A

Target

Voltage-dependent sodium channels, such as SCN8A, are responsible for the initial membrane depolarization that occurs during generation of action potentials in most electrically excitable cells.

Partner Proteins

NEDD4; MAPK14; FGF13; GNAO1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SCN8A is supported by BioGPS gene expression data to be expressed in NCIH226

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

225kDa

References & Citations

Martin, M.S., (2007) Hum. Mol. Genet. 16 (23), 2892-2899

Shipping Conditions

Wet Ice

Protein Length

1980

NCBI Gene Symbol

SCN8A

NCBI GB Accession Number

SCN8A

Host or Source

Rabbit

Protein Name

Sodium channel protein type 8 subunit alpha

Nucleotide Accession Number

NM_014191

Peptide Sequence

ESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEGC

Subunit

Alpha

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