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POU3F3 Antibody - N-terminal region : HRP (ARP33062_P050-HRP)

Selected Variant

ARP33062_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

POU class 3 homeobox 3

Gene Aliases

BRN1, OTF8, oct-8, SNIBFIS, brain-1

Gene ID

5455

Swiss Prot

P20264

Accession Number

NP_006227

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POU3F3

Target

POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') .POU3F3 is a member of the class III POU family of transcription factors (see POU3F1; MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].

Partner Proteins

Dlg4; SOX8; PPP1R15A; SOX10; SOX11; POU3F4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

POU3F3 is supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Wissmuller, S., (2006) (er) Nucleic Acids Res. 34 (6), 1735-1744

Shipping Conditions

Wet Ice

Protein Length

500

NCBI Gene Symbol

POU3F3

NCBI GB Accession Number

POU3F3

Host or Source

Rabbit

Protein Name

POU domain, class 3, transcription factor 3

Nucleotide Accession Number

NM_006236

Peptide Sequence

GGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAA

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