SMAD6 Antibody - N-terminal region : HRP (ARP32007_P050-HRP)
Selected Variant
ARP32007_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
SMAD family member 6
Gene Aliases
AOVD2, MADH6, MADH7, HsT17432
Gene ID
4091
Swiss Prot
O43541-4
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human SMAD6
Target
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
ITCH; SMURF2; BPIFA1; NEDD4L; WWP2; WWP1; USP15; USP11; PIGR; NASP; LYZ; KPNA2; CTBP2; CTBP1; UBC; ACVR1; UBE2O; BAMBI; STAMBP; ACTR1B; TGFBR1; MYD88; SMAD1; BMPR2; BMPR1B; BMPR1A; ACVR2B; ACVR1B; SMURF1; PELI1; CUL2; ELAVL1; SMAD5; RPS6KA5; TSC22D1; MAPK
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 92%; Guinea Pig: 85%; Human: 100%; Mouse: 93%; Pig: 92%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
37kDa
Shipping Conditions
Wet Ice
Protein Length
338
NCBI Gene Symbol
SMAD6
NCBI GB Accession Number
SMAD6
Host or Source
Rabbit
Protein Name
Mothers against decapentaplegic homolog 6
Peptide Sequence
RRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV
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