TFCP2 Antibody - N-terminal region: Biotin (ARP31073_P050-Biotin)

TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.

E2F8; NPEPL1; CDC73; MRPL11; KIAA1598; CBX8; TDRD1; CCDC94; ASAP3; C19orf73; FANCL; ZCCHC10; FAM64A; DNAJC27; TRAPPC12; POLL; TSPAN12; PLCB1; STMN2; MORF4L1; FARS2; EIF5B; PITPNM1; PPIG; GPANK1; BAG6; SUMO1; TCEA2; SDCBP; RBMS1; PSMD5; PPP3R2; PHF1; MRPL4

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.