ILK Antibody - C-terminal region: FITC (ARP30445_P050-FITC)
Product Specifications
Gene Name
Integrin-linked kinase
Gene Aliases
P59, ILK-1, ILK-2, p59ILK, HEL-S-28
Gene ID
3611
Swiss Prot
Q13418
Accession Number
NP_004508
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ILK
Target
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Partner Proteins
UBC; TRIM27; PARVG; PARVA; RICTOR; ITGB1; MTOR; AKT1; FKBP5; HSPH1; FAF1; CARM1; UGP2; PPAT; FBXO6; ACACA; LIMS2; RHOT1; FANCI; ATAD3A; HEATR1; CLN6; TRAFD1; ZNF568; TIMM50; RHOT2; TRABD; LPCAT1; VKORC1; RPL13; ABCE1; RBBP7; RAF1; SDF4; SEC61A1; PARVB; AK
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Goat: 82%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
49kDa
Shipping Conditions
Wet Ice
Protein Length
452
NCBI Gene Symbol
ILK
Protein Name
Integrin-linked protein kinase
Nucleotide Accession Number
NM_004517
Curated Selection
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