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KDM4D-IN-1

KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.

Product Specifications

CAS Number

2098902-68-0

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/KDM4D-IN-1.html

Purity

98.82

Solubility

DMSO : 7.14 mg/mL (ultrasonic)

Smiles

OC1=NC2=C(C#N)C(C)=NN2C3=C1C=CC=N3

Molecular Formula

C11H7N5O

Molecular Weight

225.21

Precautions

H315, H319, H335

References & Citations

[1]Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27 (14) :3201-3204.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

KDM4

Available Sizes

Frequently Asked Questions

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