COMP Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) .
Abbreviation
COMP
UniProt
P49747
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human COMP
Target
Cartilage oligomeric matrix protein (pseudoachondroplasia; epiphyseal dysplasia 1; multiple) ; Cartilage oligomeric matrix protein; Cartilage oligomeric matrix protein precursor; COMP; COMP; EDM 1; EDM1; EPD 1; EPD1; Epiphyseal dysplasia 1; Epiphyseal dysplasia 1 multiple; Epiphyseal dysplasia multiple 1; MED; MGC13181; MGC149768; PSACH; pseudoachondroplasia (epiphyseal dysplasia 1; multiple) ; Pseudoachondroplasia; THBS 5; THBS5; Thrombospondin 5; Thrombospondin-5; Thrombospondin5; TSP5
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/zhtpp9
Product MSDS
https://789.bio/eb/iTu1eL
Calculated Molecular Weight
83kDa
Citation 01
https://www.mdpi.com/2076-2615/10/12/2420
Isotype
IgG
Available Sizes
Curated Selection
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