β-Amyloid (1-16)
Product Specifications
UNSPSC Description
β-Amyloid (1-16) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
Target Antigen
Amyloid-β
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_beta_-Amyloid_1-16.html
Purity
99.98
Solubility
10 mM in H2O
Smiles
OC(C=C1)=CC=C1C[C@H](NC(CNC([C@H](CO)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@@H](N)CC(O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC4=CN=CN4)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)CCCCN)=O)=O)CC5=CN=CN5)=O)=O)=O)=O
Molecular Weight
1955.01
References & Citations
[1]Kowalik-Jankowska T, et al. Coordination abilities of the 1-16 and 1-28 fragments of beta-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study. J Inorg Biochem. 2003 Jul 1;95(4):270-82.|[2]Minicozzi V, et al. Identifying the minimal copper- and zinc-binding site sequence in amyloid-beta peptides. J Biol Chem. 2008 Apr 18;283(16):10784-92.|[3]Istrate AN, et al. NMR solution structure of rat aβ(1-16): toward understanding the mechanism of rats' resistance to Alzheimer's disease. Biophys J. 2012 Jan 4;102(1):136-43.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1466/β-Amyloid-1-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1466/β-Amyloid-1-16-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
131580-10-4
Available Sizes
Curated Selection
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