T2R49 (V129) polyclonal antibody

Product Specifications

Background

The sense of taste provides animals with valuable information about the quality and nutritional value of food. A family of G protein-coupled receptors are involved in taste perception and include T1R, which is involved in sweet and umami taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. T2R49 plays a role in sensing the chemical composition of the gastrointestinal content. T2R49 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Taste receptor type 2 member 20; Taste receptor type 2 member 49; T2R49; Taste receptor type 2 member 56; T2R56; TAS2R20; TAS2R49

Swiss Prot

P59543

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 100-150 of Human T2R49.

Conjugation

Unconjugated

Applications

WB IF

Dilution

WB: 1:500~1:1000 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 38 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

T2R49 (V129) polyclonal antibody detects endogenous levels of T2R49 protein.

Applications Notes

Western blot (WB) analysis of T2R49 (V129) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate