PTDA-PEG4-azide
Product Specifications
Product Name Alternative
PTAD-PEG4-N3
UNSPSC Description
PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ptad-peg4-n3.html
Purity
99.34
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NNC1=O)N1C2=CC=C(OCCNC(CCOCCOCCOCCOCCN=[N+]=[N-])=O)C(OC)=C2
Molecular Weight
539.54
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130940/PTDA-PEG4-azide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130940/PTDA-PEG4-azide-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2639395-40-5
Available Sizes
Curated Selection
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