TEAD-IN-12
TEAD-IN-12 (58B) is an orally active TEAD inhibitor, with an IC50 of [1].
Product Specifications
CAS Number
[3034813-66-3]
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tead-in-12.html
Smiles
CN1C=C2C=C(C=C(C2=N1)[C@H]3C[C@@H]3C(N4CC(C4)O)=O)OC5=CC=C(C=C5)C(F)(F)F
Molecular Formula
C22H20F3N3O3
Molecular Weight
431.41
References & Citations
[1]Xiao DING, et al. Tead inhibitors and methods of uses thereof. Patent. WO2024067773A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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