Thymidine 5′-diphosphate
Thymidine 5′-diphosphate (dTDP) is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg2+. Thymidine 5′-diphosphate is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP) . TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate[1][2].
Product Specifications
CAS Number
[491-97-4]
Product Name Alternative
DTDP
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/thymidine-5-diphosphate.html
Solubility
10 mM in DMSO
Smiles
O=C(N1)N([C@H]2C[C@H](O)[C@@H](COP(OP(O)(O)=O)(O)=O)O2)C=C(C)C1=O
Molecular Formula
C10H16N2O11P2
Molecular Weight
402.19
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-131576/Thymidine-5-diphosphate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-131576/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
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