CYM2503
Product Specifications
UNSPSC Description
CYM2503 is a putative GalR2-positive allosteric modulator. CYM2503 increases the latency to first electrographic seizure and decreases the total time in seizure. CYM2503 also attenuates electroshock-induced seizures in mice. Galanin receptors type 1 (GalR1) and/or type 2 (GalR2) represent unique pharmacological targets for the research of seizures and epilepsy[1].
Target Antigen
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cym2503.html
Purity
96.01
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(C=C1N2)NC([C@H](CCCCNC(OC(C)(C)C)=O)NC([C@H](CC3CCCCC3)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O)=O)=O)=CC2=O
Molecular Weight
777.95
References & Citations
[1]Lu X, et al. GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models. Proc Natl Acad Sci U S A. 2010;107(34):15229-15234.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123671/CYM2503-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123671/CYM2503-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1308833-36-4
Available Sizes
Curated Selection
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