Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Gliquidone (Standard)

Gliquidone (Standard) is the analytical standard of Gliquidone. This product is intended for research and analytical applications. Gliquidone can bind to the pancreatic β-cells and increases insulin release to regulate blood glucose levels. Gliquidone significantly decreases LPS -induced proinflammatory responses and inhibits ERK/STAT3/NF-κB phosphorylation in BV2 microglial cells. Gliquidone can suppress microgliosis, microglial hypertrophy mediated by LPS, and proinflammatory cytokine COX-2 and IL-6 levels in murine model. Gliquidone also exhibits good anticancer activity in lung carcinoma cells. Gliquidone has antioxidant property. Gliquidone can be studied in research for type 2 diabetes and cancers[1][2].

Product Specifications

CAS Number

33342-05-1

Product Name Alternative

AR-DF 26 (Standard)

UNSPSC

12352005

Target

COX; ERK; Interleukin Related; NF-κB; Potassium Channel; Reference Standards; STAT

Type

Reference Standards

Related Pathways

Immunology/Inflammation; JAK/STAT Signaling; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; NF-κB; Others; Stem Cell/Wnt

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gliquidone-standard.html

Smiles

O=S(C1=CC=C(CCN(C(C(C)(C)C2=C3C=C(OC)C=C2)=O)C3=O)C=C1)(NC(NC4CCCCC4)=O)=O

Molecular Formula

C27H33N3O6S

Molecular Weight

527.63

References & Citations

[1]Kim, J., et al., (2021) . The Anti-diabetic Drug Gliquidone Modulates Lipopolysaccharide-Mediated Microglial Neuroinflammatory Responses by Inhibiting the NLRP3 Inflammasome. Frontiers in aging neuroscience, 13, 754123. |[2]M. Shamona, et al., Vibrational spectra of second generation antidiabetic drug gliquidone exhibiting anticancer activity, antioxidant activity using both the experimental and theoretical approach, Journal of Molecular Liquids, Volume 411, 2024.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CPT2, NT (Carnitine O-palmitoyltransferase 2, Mitochondrial, Carnitine Palmitoyltransferase II, CPT II, CPT1) (AP) discontinued
C1385-50A-AP 200 µL

CPT2, NT (Carnitine O-palmitoyltransferase 2, Mitochondrial, Carnitine Palmitoyltransferase II, CPT II, CPT1) (AP) discontinued

Sign In for Pricing
View Details
Garcinol
SIH-355-5MG 5 mg

Garcinol

Sign In for Pricing
View Details
ARTN CRISPR All-in-one AAV vector set (with saCas9)(Human)
12482151 3x 1.0 µg DNA

ARTN CRISPR All-in-one AAV vector set (with saCas9)(Human)

Sign In for Pricing
View Details
Human Soluble Lectin-like oxidized low density lipoprotein receptor-1 (sLOX-1) ELISA Kit
201-12-1425 96 Tests

Human Soluble Lectin-like oxidized low density lipoprotein receptor-1 (sLOX-1) ELISA Kit

Sign In for Pricing
View Details
ZNT8 Polyclonal Antibody, HRP Conjugated
bs-15382R-HRP 100 µL

ZNT8 Polyclonal Antibody, HRP Conjugated

Sign In for Pricing
View Details
Recombinant Human GSK3B Protein, His, E.coli-500ug
QP6121-ec-500ug 500ug

Recombinant Human GSK3B Protein, His, E.coli-500ug

Sign In for Pricing
View Details