Autophagy-IN-4
Autophagy-IN-4 (Compound 34) is an autophagy inhibitor, with an EC50 of 0.5 μM and a LD50 of 27 μM for U2OS cells[1].
Product Specifications
CAS Number
[1411646-44-0]
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/autophagy-in-4.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C2C(N=C3CCCCC3=C2NCCN4CCN(CC4)C)=C1
Molecular Formula
C20H27ClN4
Molecular Weight
358.91
References & Citations
[1]Wang et al. Synthesis of improved lysomotropic autophagy inhibitors. J Med Chem. 2015 Apr 9;58 (7) :3025-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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