Etbicyphat-13C3

Etbicyphat-13C3 is the 13C labeled Etbicyphat (HY-139145) . Etbicyphat is a potent GABA (A) receptors competitive antagonist. Etbicyphat induces epileptiform activities in hippocampal CA1 neurons, and binds to the GABA (A) -benzodiazepine receptors[1][2].

Product Specifications

CAS Number

[2300178-69-0]

Product Name Alternative

Trimethylopropane phosphate-13C3

UNSPSC

12352005

Target

GABA Receptor

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/etbicyphat-13c3.html

Solubility

10 mM in DMSO

Smiles

CC[13C](CO1)([13CH2]O2)[13CH2]O[P]12=O

Molecular Formula

C3 13C3H11O4P

Molecular Weight

181.10

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Rijal SO, et al. Dissociation constants for GABA (A) receptor antagonists determined with neuronal networks on microelectrode arrays. J Neurosci Methods. 2008 Aug 30;173 (2) :183-92.