Recombinant Rat KLK6 Protein (His Tag)
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Abbreviation
KLK6
Synonyms
Bssp; KLK 6; KLK6; KLK9; Kallikrein 6 precursor; Kallikrein related peptidase 6; Kallikrein-6; Kallikrein6; Klk29; Klk6; Klk7; MGC9355; MSP; Neurosin; PRSS 18; PRSS 9; PRSS18; PRSS9; Protease M; Protease serine 18; Protease serine 9; Serine prote; hK 6; hK6; mGK 1; mGK1
UniProt
P36374
Accession Number
P36374-1
Expression System
E.coli
Tag
N-His
Sequence
Ile25-Pro261
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 80% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
26.3 kDa
Observed Molecular Weight
28.62 kDa
Species
Rat
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items