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XYLT1 rabbit pAb

This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum. [provided by RefSeq, Nov 2009],

Product Specifications

Background

This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]

Synonyms

Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I) (XT-I) (XylT-I)

Gene ID

64131

UniProt

Q86Y38

Cellular Locus

Golgi apparatus membrane ; Single-pass type II membrane protein. Secreted. Detected predominantly in the Golgi apparatus..

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human XYLT1 AA range: 312-362

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB

Validated Applications

WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000

Molecular Weight

105kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES12272-1.pdf

Observed Molecular Weight

105 kD

Subcellular Location

Golgi apparatus membrane ; Single-pass type II membrane protein . Secreted . Detected predominantly in the Golgi apparatus. .

Other Product Names

Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I) (XT-I) (XylT-I)

Gene ID (Human)

64131

SwissProt (Human)

Q86Y38

Available Sizes

Curated Selection

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