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Recombinant Mouse PGR protein (His tag)

Product Specifications

Background

Progesterone Receptor B (PR-B) is a 118 kDa member of the NR3 subfamily within the nuclear hormone receptor family of proteins. It is expressed in female reproductive tissues as well as neurons throughout the CNS. PR-B is particularly important in the mammary gland where it mediates proliferative responses to progesterone.

Abbreviation

PGR

Synonyms

Nuclear receptor subfamily 3 group C member 3; Pgr; Progesterone receptor

UniProt

Q00175

Accession Number

Q00175

Expression System

E.coli

Tag

N-His

Sequence

Ile 681-Lys 926

Field of Research

Cancer; Epigenetics and Nuclear signaling; Neuroscience; signal Transduction; Biochemicals

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

27.0 kDa

Observed Molecular Weight

30 kDa

Species

Mouse

Available Sizes

Frequently Asked Questions

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