Recombinant CD68 Monoclonal Antibody
Product Specifications
Background
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
Abbreviation
CD68
UniProt
P34810
Host
Rabbit
Reactivity
Human; Cynomolgus
Immunogen
Recombinant Human CD68 Protein
Target
SRD; LAMP; DKFZp686M; MACROPHAGE ANTIGEN CD; CD68 antigenmacrophage antigen CD; Scavenger receptor class D member; SR-D; SCARD; CD68; GP110; LAMP4; SCARD1; CD 68; CD68 antigen; CD68 antigenmacrophage antigen CD68; CD68 molecule; DKFZp686M18236; gp11; MACROPHAGE ANTIGEN CD68; Macrophage antigen CD68 (microsialin) ; Macrosialin; Scavenger receptor class D member 1; SRD1; SR-D1; gp110; CD 68; CD68; CD68 antigen; CD68 molecule; CD68; DKFZp686M18236; gp11; Gp110; LAMP4; Macrophage antigen CD68 (microsialin) ; MACROPHAGE ANTIGEN CD68; Macrosialin; SCARD1; Scavenger receptor class D member 1
Clonality
Monoclonal
Clone
1F8
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Immunology
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:60-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/2om68xjx
Product MSDS
https://789.bio/eb/X2l3amQd
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items