TESC (NM_017899) Human Recombinant Protein
Product Specifications
Background
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na (+) /H (+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.[UniProtKB/Swiss-Prot Function]
Synonyms
CHP3; TSC
Gene ID
54997
UniProt
Q96BS2
Accession Number mRNA
NM_017899
Chromosomal Location
12q24.22
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
24.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TESC
Species
Human
Protein ID
NP_060369
Overview
Recombinant protein of human tescalcin (TESC)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54997
Uniprot URL
https://www.uniprot.org/uniprot/Q96BS2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017899
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060369
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