Recombinant CD27/TNFRSF7 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Abbreviation
CD27
UniProt
P26842
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human CD27/TNFRSF7 Protein
Target
S152. LPFS; T-cell activation antigen CD; TNFRSF; S152.LPFS; CD27; S152; S152. LPFS2; T14; TNFRSF7; Tp55; S152.LPFS2; CD27L receptor; T-cell activation antigen CD27; S152; TNFRSF7; CD 27; CD27 antigen; CD27 molecule; LPFS2; MGC20393; OTTHUMP00000238557; T cell activation antigen CD27; T cell antivation antigen S152; TNFRSF 7; TNFSF7; Tp 55; Tumor necrosis factor receptor superfamily member 7
Clonality
Monoclonal
Clone
2B8
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology; Cancer; Stem Cells
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/g0nr008b
Product MSDS
https://789.bio/eb/MRjVApQx
Calculated Molecular Weight
29 kDa
Observed Molecular Weight
65 kDa
Isotype
IgG
Curated Selection
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